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post-doctorats en ostéoimmunologie et immunologie à Nice

2-3-year postdoctoral position in osteoimmunology
in Nice, France


We are seeking a highly motivated and talented post-doctoral researcher to join our team and
work on the ORIOS project founded by the French National Research Agency
Host laboratory: The team "Osteoimmunology, niches and inflammation" in the
Laboratory of Molecular PhysioMedicine, Nice, France (http://unice.fr/lp2m/fr/lesequipes/
osteoimmunologie-niche-inflammation-c-blin) is depending on the CNRS, the main
research body in France, and the University of Nice labeled as "University of Excellence".
Located in the Faculty of Medicine in the heart of Nice, it provides a high-quality scientific
environment with access to all required core facilities as well as interaction with clinicians.
Project:
The research activities of the team are focused on the cellular interactions between immune and
non-immune cells in the bone marrow. Among these cells, osteoclasts are monocytic boneresorbing
cells responsible for bone destruction in many chronic inflammatory diseases. We have
recently shown that their function is not limited to bone resorption and that depending on their
origin and environment, they induce immunosuppressive or inflammatory responses.
The post-doc will participate to the ORIOS project "Origin and role of inflammatory osteoclasts,
novel therapeutic targets in rheumatic diseases" recently founded by the French National
Research Agency (ANR). The objectives of this project are an in-depth characterization of
inflammatory and tolerogenic osteoclasts in terms of their origin, function and specific markers
to understand their contribution to inflammatory responses and to modifications of the bone
marrow integrity. The project combines analysis in vitro, in vivo in murine models of chronic
diseases associated with bone destruction and in patients. The aim is to identify new clues for
diagnosis and therapeutic strategies as well as novel information on a neglected aspect of
osteoclast biology.
Requirements:
We are seeking a highly motivated and talented post-doctoral researcher with a strong
background in osteoimmunology, immunology or bone biology, assessed by publications. She/
he must have a strong experience in cell biology, flow cytometry and animal experimentation.
Ability to work independently, and excellent team, communication and organization skills are
essential. French or English practice is mandatory. The salary is according to the rules of the
French public service and depends on the experience (30 to 45k€ annual gross).
The position is founded for 2 years with a possibility to extend for 1 more year depending on the
results and the level of salary. It represents an excellent opportunity for a young scientist to
develop/extend expertise in osteoimmunology. In addition to an excellent scientific production,
if independent thinking and capacity to undertake responsibility as project leader are proven,
the postdoc will be supported to apply for a permanent position in the team.
To apply:
Applicants should submit (in French or in English) their CV and publication list, the name and email
of 3 references and a brief statement of past achievements and research interests to Dr Blin
(blin@unice.fr). Deadline for application: no later than October 30, 2017.
Starting: Beginning of 2018.

 

 

 

 

Postdoctoral position in CD4+ T cell biology, Nice,
France
We are looking for a highly motivated and enthusiastic post-doctoral researcher with a strong
background in immunology to participate in a project founded by an industrial partnership and
focusing on the effect of biotherapies on the balance between inflammatory and antiinflammatory
CD4+ T cells in the context of rheumatic diseases.
Host laboratory: The team "Osteoimmunology, niches and inflammation" in the
Laboratory of Molecular PhysioMedicine, Nice, France (http://unice.fr/lp2m/fr/lesequipes/
osteoimmunologie-niche-inflammation-c-blin) is depending on the CNRS, the main
research body in France, and the University of Nice labeled as "University of Excellence".
Located in the Faculty of Medicine in the heart of Nice, it provides a high-quality scientific
environment with access to all required core facilities as well as interaction with clinicians.
Project:
The research activities of the team are focused on the cellular interactions between immune and
non-immune cells and in particular in the dialog between the bone marrow and the gut. The
postdoctoral researcher will work on the effect of biotherapies on CD4+ T cell polarization in
relation with microbiota dysbiosis. The project combines analysis in vitro, in vivo in a murine
model of inflammatory bowel disease and in patients affected with Crohn's disease.
The position is founded for 1 year starting from January 1st, 2018, with a possibility to extend for
1 more year depending on the results.
Requirements:
The candidate should have a strong background in immunology assessed by publications.
Expertise in microbiota analysis is an advantage. He/she should have very good experience in
animal experimentation, analysis of immune cells from patients, flow cytometry, cell culture and
T cell biology. He/she should be able to work independently. Excellent presentation and team
skills are also required.
French or English practice is mandatory. The salary is according to the rules of the French public
service and depends on the experience (30 to 45k€ annual gross).
To apply:
Applicants should submit (in French or in English) their CV and publication list, the name and email
of 3 references and a brief statement of past achievements and research interests to Dr
Wakkach (wakkach@unice.fr). Deadline for application: no later than October 30, 2017.